Mendel was aboard The Simpsons from its launch in 1989, coming from The Tracey UIllman Show. Between 1989 and 1999, he was credited as a producer on 207 episodes, winning three Emmys. He earned a fourth Emmy in 2018 as a line producer on Rick and Morty. "My friend, partner, and line producer Mike Mendel passed away. I am devastated," tweeted Rick and Morty co-creator Justin Roiland. "My heart breaks for his family. I don’t know what I’m going to do without you by my side Mike. I’m destroyed."